SCOP 1.69: Domain d2cd0b_: 2cd0 B:

Lineage for d2cd0b_ (2cd0 B:)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
   VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family

7. Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (4 PDB entries)

8. Domain d2cd0b_: 2cd0 B: [20562]
   VL dimer of Bence-Jones protein WIL

Details for d2cd0b_

PDB Entry: 2cd0, 1.8 Å

PDB Description: structure of human lambda-6 light chain dimer wil

SCOP Domain Sequences for d2cd0b_:

Sequence; same for both SEQRES and ATOM records:

>d2cd0b_ b.1.1.1 (B:) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 1}
nflltqphsvsespgktvtisctrssgsiannyvhwyqqrpgsspttvifeddhrpsgvp
drfsgsvdtssnsasltisglktedeadyycqsydhnnqvfgggtkltvlg

Timeline for d2cd0b_:

• d2cd0b_ first appeared (with stable ids) in SCOP 1.55
  
• d2cd0b_ appears in SCOP 1.67
  
• d2cd0b_ appears in SCOP 1.71
  
• d2cd0b_ appears in the current release, SCOPe 2.08