SCOPe 2.03: Domain d2p2nd_: 2p2n D:

Lineage for d2p2nd_ (2p2n D:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.88: Glutaminase/Asparaginase [53773] (1 superfamily)
   consists of two non-similar alpha/beta domains, 3 layers (a/b/a) each
   Domain 1 has mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest; left-handed crossover connection between strands 4 and 5
   Domain 2 has parallel beta-sheet of 4 strands, order 1234

4. Superfamily c.88.1: Glutaminase/Asparaginase [53774] (2 families)

5. Family c.88.1.1: Glutaminase/Asparaginase [53775] (4 proteins)
   automatically mapped to Pfam PF00710

6. Protein automated matches [190446] (4 species)
   not a true protein

7. Species Escherichia coli [TaxId:562] [225264] (3 PDB entries)

8. Domain d2p2nd_: 2p2n D: [205434]
   automated match to d3ntxa_
   complexed with asn, asp, cl, edo

Details for d2p2nd_

PDB Entry: 2p2n, 1.9 Å

PDB Description: Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I

PDB Compounds: (D:) L-asparaginase I

SCOPe Domain Sequences for d2p2nd_:

Sequence, based on SEQRES records:

>d2p2nd_ c.88.1.1 (D:) automated matches {Escherichia coli [TaxId: 562]}
vprgshmqkksiyvaytggtigmqrseqgyipvsghlqrqlalmpefhrpempdftihey
tplmdssdmtpedwqhiaedikahyddydgfvilhgtdtmaytasalsfmlenlgkpviv
tgsqiplaelrsdgqinllnalyvaanypinevtlffnnrlyrgnrttkahadgfdafas
pnlpplleagihirrlntppaphgegelivhpitpqpigvvtiypgisadvvrnflrqpv
kalilrsygvgnapqnkaflqelqeasdrgivvvnltqcmsgkvnmggyatgnalahagv
iggadmtveatltklhyllsqeldtetirkamsqnlrgeltpd

Sequence, based on observed residues (ATOM records):

>d2p2nd_ c.88.1.1 (D:) automated matches {Escherichia coli [TaxId: 562]}
vprgshmqkksiyvaytgghlqrqlalmpefhrpempdftiheytplmdssdmtpedwqh
iaedikahyddydgfvilhgtdtmaytasalsfmlenlgkpvivtgsqiplaelrsdgqi
nllnalyvaanypinevtlffnnrlyrgnrttkahadgfdafaspnlpplleagihirrl
ntppaphgegelivhpitpqpigvvtiypgisadvvrnflrqpvkalilrsygvgnapqn
kaflqelqeasdrgivvvnltqcmsgkvnalahagviggadmtveatltklhyllsqeld
tetirkamsqnlrgeltpd

Timeline for d2p2nd_:

• d2p2nd_ is new in SCOPe 2.03-stable
  
• d2p2nd_ appears in SCOPe 2.04
  
• d2p2nd_ appears in the current release, SCOPe 2.08, called d2p2nd1