SCOPe 2.05: Domain d2ns7d2: 2ns7 D:68-205

Lineage for d2ns7d2 (2ns7 D:68-205)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
   multihelical; interlocked (homo)dimer

4. Superfamily a.121.1: Tetracyclin repressor-like, C-terminal domain [48498] (2 families)

5. Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain [48499] (35 proteins)

6. Protein Tetracyclin repressor (Tet-repressor, TetR) [48500] (1 species)

7. Species Escherichia coli [TaxId:562] [48501] (23 PDB entries)

8. Domain d2ns7d2: 2ns7 D:68-205 [205154]
   Other proteins in same PDB: d2ns7a1, d2ns7b1, d2ns7c1, d2ns7d1
   automated match to d1qpia2

Details for d2ns7d2

PDB Entry: 2ns7, 2.4 Å

PDB Description: how an in vitro selected peptide mimics the antibiotic tetracycline to induce tet repressor

PDB Compounds: (D:) Tetracycline repressor protein

SCOPe Domain Sequences for d2ns7d2:

Sequence, based on SEQRES records:

>d2ns7d2 a.121.1.1 (D:68-205) Tetracyclin repressor (Tet-repressor, TetR) {Escherichia coli [TaxId: 562]}
splegeswqdflrnnaksfrnallshrdgakvhlgtrptekqyetlenqlafltqqgfsl
enalyalsavghftlgsvledqehqvakeeretpttdsmppllrqaielfdhqgaepafl
hgleslirgfevqltall

Sequence, based on observed residues (ATOM records):

>d2ns7d2 a.121.1.1 (D:68-205) Tetracyclin repressor (Tet-repressor, TetR) {Escherichia coli [TaxId: 562]}
splegeswqdflrnnaksfrnallshrdgakvhlgtrptekqyetlenqlafltqqgfsl
enalyalsavghftlgsvledqehqvakegaepaflhgleslirgfevqltall

Timeline for d2ns7d2:

• d2ns7d2 first appeared in SCOPe 2.03
  
• d2ns7d2 appears in SCOPe 2.04
  
• d2ns7d2 appears in SCOPe 2.06
  
• d2ns7d2 appears in the current release, SCOPe 2.08