Lineage for d2hwoa_ (2hwo A:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2586455Protein c-src tyrosine kinase [56155] (3 species)
    PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase
  7. 2586456Species Chicken (Gallus gallus) [TaxId:9031] [56157] (54 PDB entries)
  8. 2586539Domain d2hwoa_: 2hwo A: [204651]
    automated match to d2gqgb_
    complexed with gol, rbs

Details for d2hwoa_

PDB Entry: 2hwo (more details), 2.5 Å

PDB Description: crystal structure of src kinase domain in complex with covalent inhibitor
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d2hwoa_:

Sequence, based on SEQRES records: (download)

>d2hwoa_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
lakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvm
kklrheklvqlyavvseepiyivteymskgclldflkgemgkylrlpqlvdmaaqiasgm
ayvermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaa
lygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdl
mcqcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records): (download)

>d2hwoa_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
lakdaweipreslrlevklggcfgevwmgtwngttrvaiktlkpflqeaqvmkklrhekl
vqlyavvspiyivteymskgclldflkgemgkylrlpqlvdmaaqiasgmayvermnyvh
rdlraanilvgenlvckvadfgpikwtapeaalygrftiksdvwsfgilltelttkgrvp
ypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyfts
tepqyqpgenl

SCOPe Domain Coordinates for d2hwoa_:

Click to download the PDB-style file with coordinates for d2hwoa_.
(The format of our PDB-style files is described here.)

Timeline for d2hwoa_: