SCOPe 2.08: Domain d2hw7a1: 2hw7 A:72-371

Lineage for d2hw7a1 (2hw7 A:72-371)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d2hw7a1: 2hw7 A:72-371 [204644]
   Other proteins in same PDB: d2hw7a2
   automated match to d4gcja_
   complexed with stu, zn

Details for d2hw7a1

PDB Entry: 2hw7, 2.71 Å

PDB Description: crystal structure of mnk2-d228g in complex with staurosporine

PDB Compounds: (A:) MAP kinase-interacting serine/threonine-protein kinase 2

SCOPe Domain Sequences for d2hw7a1:

Sequence, based on SEQRES records:

>d2hw7a1 d.144.1.0 (A:72-371) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tdsfsgrfedvyqlqedvlgegaharvqtcinlitsqeyavkiiekqpghirsrvfreve
mlyqcqghrnvlelieffeeedrfylvfekmrggsilshihkrrhfneleasvvvqdvas
aldflhnkgiahrdlkpenilcehpnqvspvkicdfglgsgiklngdcspistpelltpc
gsaeymapevveafseeasiydkrcdlwslgvilyillsgyppfvgrcgsdcgwdrgeac
pacqnmlfesiqegkyefpdkdwahiscaakdliskllvrdakqrlsaaqvlqhpwvqgc

Sequence, based on observed residues (ATOM records):

>d2hw7a1 d.144.1.0 (A:72-371) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tdsfsgrfedvyqlqedvlgegaharvqtcinlitsqeyavkiiekqpghirsrvfreve
mlyqcqghrnvlelieffeeedrfylvfekmrggsilshihkrrhfneleasvvvqdvas
aldflhnkgiahrdlkpenilcehpnqvspvkicdfggsaeymapevveafseeasiydk
rcdlwslgvilyillsgyppfvgrccgacpacqnmlfesiqegkyefpdkdwahiscaak
dliskllvrdakqrlsaaqvlqhpwvqgc

Timeline for d2hw7a1:

• d2hw7a1 first appeared in SCOPe 2.03, called d2hw7a_
  
• d2hw7a1 appears in SCOPe 2.07