Lineage for d2hiwa1 (2hiw A:248-517)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2545120Protein automated matches [190091] (19 species)
    not a true protein
  7. 2545220Species Human (Homo sapiens) [TaxId:9606] [188447] (741 PDB entries)
  8. 2545639Domain d2hiwa1: 2hiw A:248-517 [204564]
    Other proteins in same PDB: d2hiwa2, d2hiwb2
    automated match to d1opja_
    complexed with 7mp

Details for d2hiwa1

PDB Entry: 2hiw (more details), 2.2 Å

PDB Description: Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2hiwa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hiwa1 d.144.1.7 (A:248-517) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaav
mkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqiss
ameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtape
slaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvy
elmracwqwnpsdrpsfaeihqafetmfqe

SCOPe Domain Coordinates for d2hiwa1:

Click to download the PDB-style file with coordinates for d2hiwa1.
(The format of our PDB-style files is described here.)

Timeline for d2hiwa1:

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Domains from same chain:
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d2hiwa2