SCOPe 2.08: Domain d2hima_: 2him A:

Lineage for d2hima_ (2him A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.88: Glutaminase/Asparaginase [53773] (1 superfamily)
   consists of two non-similar alpha/beta domains, 3 layers (a/b/a) each
   Domain 1 has mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest; left-handed crossover connection between strands 4 and 5
   Domain 2 has parallel beta-sheet of 4 strands, order 1234

4. Superfamily c.88.1: Glutaminase/Asparaginase [53774] (2 families)

5. Family c.88.1.1: Glutaminase/Asparaginase [53775] (4 proteins)
   automatically mapped to Pfam PF00710

6. Protein automated matches [190446] (8 species)
   not a true protein

7. Species Escherichia coli [TaxId:562] [225264] (3 PDB entries)

8. Domain d2hima_: 2him A: [204560]
   Other proteins in same PDB: d2himb2, d2himd2
   automated match to d3ntxa_
   complexed with asn, asp, edo

Details for d2hima_

PDB Entry: 2him, 1.82 Å

PDB Description: crystal structure and allosteric regulation of the cytoplasmic escherichia coli l-asparaginase i

PDB Compounds: (A:) L-asparaginase 1

SCOPe Domain Sequences for d2hima_:

Sequence, based on SEQRES records:

>d2hima_ c.88.1.1 (A:) automated matches {Escherichia coli [TaxId: 562]}
kksiyvaytggtigmqrseqgyipvsghlqrqlalmpefhrpempdftiheytplmdssd
mtpedwqhiaedikahyddydgfvilhgtdtmaytasalsfmlenlgkpvivtgsqipla
elrsdgqinllnalyvaanypinevtlffnnrlyrgnrtakahadgfdafaspnlpplle
agihirrlntppaphgegelivhpitpqpigvvtiypgisadvvrnflrqpvkalilrsy
gvgnapqnkaflqelqeasdrgivvvnltqcmsgkvnmggyatgnalahagviggadmtv
eatltklhyllsqeldtetirkamsqnlrgeltp

Sequence, based on observed residues (ATOM records):

>d2hima_ c.88.1.1 (A:) automated matches {Escherichia coli [TaxId: 562]}
kksiyvaytggtigmqripvsghlqrqlalmpefhrpempdftiheytplmdssdmtped
wqhiaedikahyddydgfvilhgtdtmaytasalsfmlenlgkpvivtgsqiplaelrsd
gqinllnalyvaanypinevtlffnnrlyrgnrtakahadgfdafaspnlpplleagihi
rrlntppaphgegelivhpitpqpigvvtiypgisadvvrnflrqpvkalilrsygvgna
pqnkaflqelqeasdrgivvvnltqcmsgkvnmgnalahagviggadmtveatltklhyl
lsqeldtetirkamsqnlrgeltp

Timeline for d2hima_:

• d2hima_ first appeared in SCOPe 2.03
  
• d2hima_ appears in SCOPe 2.07