Lineage for d1f4xh1 (1f4x H:1-117)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017693Species Mouse (Mus musculus), cluster 2.2 [TaxId:10090] [88550] (59 PDB entries)
    Uniprot P01811 # HV41_MOUSE (P01811) Ig heavy chain V region UPC10
  8. 2017711Domain d1f4xh1: 1f4x H:1-117 [20451]
    Other proteins in same PDB: d1f4xh2, d1f4xl1, d1f4xl2
    part of anti-carbohydrate Fab S-20-4
    complexed with mgs

Details for d1f4xh1

PDB Entry: 1f4x (more details), 2.3 Å

PDB Description: crystal structure of an anti-carbohydrate antibody directed against vibrio cholerae o1 in complex with antigen
PDB Compounds: (H:) antibody s-20-4, fab fragment, heavy chain

SCOPe Domain Sequences for d1f4xh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1f4xh1 b.1.1.1 (H:1-117) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 2.2 [TaxId: 10090]}

SCOPe Domain Coordinates for d1f4xh1:

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Timeline for d1f4xh1:

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