SCOPe 2.07: Domain d2gb4b_: 2gb4 B:

Lineage for d2gb4b_ (2gb4 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.36: Thiopurine S-methyltransferase [102566] (1 protein)
   automatically mapped to Pfam PF05724

6. Protein Thiopurine S-methyltransferase [102567] (3 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [225137] (3 PDB entries)

8. Domain d2gb4b_: 2gb4 B: [204322]
   automated match to d2bzga1
   complexed with sah

Details for d2gb4b_

PDB Entry: 2gb4, 1.25 Å

PDB Description: Crystal structure of Thiopurine methyltransferase (18204406) from Mus musculus at 1.35 A resolution

PDB Compounds: (B:) thiopurine s-methyltransferase

SCOPe Domain Sequences for d2gb4b_:

Sequence; same for both SEQRES and ATOM records:

>d2gb4b_ c.66.1.36 (B:) Thiopurine S-methyltransferase {Mouse (Mus musculus) [TaxId: 10090]}
aevqknqvltledwkekwvtrhisfhqeqghqllkkhldtflkgqsglrvffplcgkaie
mkwfadrghtvvgveiseigireffaeqnlsyteeplaeiagakvfksssgsislyccsi
fdlpranigkfdriwdrgalvainpgdhdryadiilsllrkefqylvavlsydptkhagp
pfyvpsaelkrlfgtkcsmqcleevdaleerhkawgldylfeklylltek

Timeline for d2gb4b_:

• d2gb4b_ first appeared in SCOPe 2.03
  
• d2gb4b_ appears in SCOPe 2.06