Lineage for d2cjza_ (2cjz A:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1851756Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 1851757Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 1852137Family c.45.1.0: automated matches [191381] (1 protein)
    not a true family
  6. 1852138Protein automated matches [190475] (8 species)
    not a true protein
  7. 1852150Species Human (Homo sapiens) [TaxId:9606] [187400] (99 PDB entries)
  8. 1852169Domain d2cjza_: 2cjz A: [203799]
    automated match to d2hvla_
    complexed with edo, ptr; mutant

Details for d2cjza_

PDB Entry: 2cjz (more details), 1.7 Å

PDB Description: crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine
PDB Compounds: (A:) human protein tyrosine phosphatase ptpn5

SCOPe Domain Sequences for d2cjza_:

Sequence, based on SEQRES records: (download)

>d2cjza_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nlyfqsmsrvlqaeelhekaldpfllqaeffeipmnfvdpkeydipglvrknryktilpn
phsrvcltspdpddplssyinanyirgyggeekvyiatqgpivstvadfwrmvwqehtpi
ivmitnieemnekcteywpeeqvaydgveitvqkvihtedyrlrlislksgteerglkhy
wftswpdqktpdrappllhlvreveeaaqqegphcapiivhssagigrtgcfiatsiccq
qlrqegvvdilkttcqlrqdrggmiqtceqyqfvhhvmslyekqls

Sequence, based on observed residues (ATOM records): (download)

>d2cjza_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nlyfqsmsrvlqaeelhekaldpfllqaeffeipmnfvdpkeydipglvrknryktilpn
phsrvcltspdpddplssyinanyirgyggeekvyiatqgpivstvadfwrmvwqehtpi
ivmitteywpeeqvaydgveitvqkvihtedyrlrlislkseerglkhywftswpdqktp
drappllhlvreveeaaqqegphcapiivhssagigrtgcfiatsiccqqlrqegvvdil
kttcqlrqdrggmiqtceqyqfvhhvmslyekqls

SCOPe Domain Coordinates for d2cjza_:

Click to download the PDB-style file with coordinates for d2cjza_.
(The format of our PDB-style files is described here.)

Timeline for d2cjza_: