![]() | Class b: All beta proteins [48724] (126 folds) |
![]() | Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
![]() | Superfamily b.1.1: Immunoglobulin [48726] (4 families) ![]() |
![]() | Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins) |
![]() | Protein Immunoglobulin heavy chain variable domain, VH [88543] (19 species) VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogeneous CDRs are listed as engineered species |
![]() | Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (22 PDB entries) |
![]() | Domain d1sm3h1: 1sm3 H:1-113 [20369] Other proteins in same PDB: d1sm3h2, d1sm3l1, d1sm3l2 part of tumor-specific Fab SM3 against epithelial mucin Muc1 complexed with cd, cl |
PDB Entry: 1sm3 (more details), 1.95 Å
SCOP Domain Sequences for d1sm3h1:
Sequence; same for both SEQRES and ATOM records: (download)
>d1sm3h1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 1} qvqlqesggglvqpggsmklscvasgftfsnywmnwvrqspekglewvaeirlksnnyat hyaesvkgrftisrddskssvylqmnnlraedtgiyyctgvgqfaywgqgttvtvss
Timeline for d1sm3h1: