SCOPe 2.08: Domain d2c0ya_: 2c0y A:

Lineage for d2c0ya_ (2c0y A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein automated matches [190264] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187102] (9 PDB entries)

8. Domain d2c0ya_: 2c0y A: [203682]
   automated match to d1by8a_
   mutant

Details for d2c0ya_

PDB Entry: 2c0y, 2.1 Å

PDB Description: the crystal structure of a cys25ala mutant of human procathepsin s

PDB Compounds: (A:) procathepsin s

SCOPe Domain Sequences for d2c0ya_:

Sequence, based on SEQRES records:

>d2c0ya_ d.3.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lhkdptldhhwhlwkktygkqykekneeavrrliweknlkfvmlhnlehsmgmhsydlgm
nhlgdmtseevmslmsslrvpsqwqrnityksnpnrilpdsvdwrekgcvtevkyqgscg
aawafsavgaleaqlklktgklvslsaqnlvdcstekygnkgcnggfmttafqyiidnkg
idsdasypykamdqkcqydskyraatcskytelpygredvlkeavankgpvsvgvdarhp
sfflyrsgvyyepsctqnvnhgvlvvgygdlngkeywlvknswghnfgeegyirmarnkg
nhcgiasfpsypei

Sequence, based on observed residues (ATOM records):

>d2c0ya_ d.3.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lhkdptldhhwhlwkktygkqykekneeavrrliweknlkfvmlhnlehsmgmhsydlgm
nhlgdmtseevmslmsslrvpsqwqrnityilpdsvdwrekgcvtevkyqgscgaawafs
avgaleaqlklktgklvslsaqnlvdcstekygnkgcnggfmttafqyiidnkgidsdas
ypykamdqkcqydskyraatcskytelpygredvlkeavankgpvsvgvdarhpsfflyr
sgvyyepsctqnvnhgvlvvgygdlngkeywlvknswghnfgeegyirmarnkgnhcgia
sfpsypei

Timeline for d2c0ya_:

• d2c0ya_ first appeared in SCOPe 2.03
  
• d2c0ya_ appears in SCOPe 2.07