SCOPe 2.06: Domain d1qbmh1: 1qbm H:1-117

Lineage for d1qbmh1 (1qbm H:1-117)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] [88551] (31 PDB entries)
   SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form)

8. Domain d1qbmh1: 1qbm H:1-117 [20365]
   Other proteins in same PDB: d1qbmh2, d1qbml1, d1qbml2
   part of anti-cytochrome c Fab E8

Details for d1qbmh1

PDB Entry: 1qbm, 2.37 Å

PDB Description: fab e8b antibody, x-ray structure at 2.37 angstroms resolution

PDB Compounds: (H:) e8b antibody

SCOPe Domain Sequences for d1qbmh1:

Sequence; same for both SEQRES and ATOM records:

>d1qbmh1 b.1.1.1 (H:1-117) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.1 [TaxId: 10090]}
evqlqqsgaelvkpgasvklsctasgfnikdtymhwvkqrpekglewigridpasgntky
dpkfqdkatitadtssntaylqlssltsedtavyycagydygnfdywgqgttltvss

Timeline for d1qbmh1:

• d1qbmh1 first appeared (with stable ids) in SCOP 1.55
  
• d1qbmh1 appears in SCOPe 2.05
  
• d1qbmh1 appears in SCOPe 2.07
  
• d1qbmh1 appears in the current release, SCOPe 2.08