SCOPe 2.02: Domain d1wejh1: 1wej H:1-112

Lineage for d1wejh1 (1wej H:1-112)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] [88551] (31 PDB entries)
   SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form)

8. Domain d1wejh1: 1wej H:1-112 [20361]
   Other proteins in same PDB: d1wejf_, d1wejh2, d1wejl1, d1wejl2
   part of anti-cytochrome c Fab E8
   complexed with hem, zn

Details for d1wejh1

PDB Entry: 1wej, 1.8 Å

PDB Description: igg1 fab fragment (of e8 antibody) complexed with horse cytochrome c at 1.8 a resolution

PDB Compounds: (H:) e8 antibody

SCOPe Domain Sequences for d1wejh1:

Sequence; same for both SEQRES and ATOM records:

>d1wejh1 b.1.1.1 (H:1-112) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.1 [TaxId: 10090]}
evqlqqsgaelvkpgasvklsctasgfnikdtymhwvkqrpekglewigridpasgntky
dpkfqdkatitadtssntaylqlssltsedtavyycagydygnfdywgqgtt

Timeline for d1wejh1:

• d1wejh1 first appeared (with stable ids) in SCOP 1.55
  
• d1wejh1 appears in SCOPe 2.01
  
• d1wejh1 appears in SCOPe 2.03
  
• d1wejh1 appears in the current release, SCOPe 2.08