SCOPe 2.07: Domain d2ab2b_: 2ab2 B:

Lineage for d2ab2b_ (2ab2 B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (155 PDB entries)

8. Domain d2ab2b_: 2ab2 B: [203436]
   automated match to d2aa6b_
   complexed with snl, so4; mutant

Details for d2ab2b_

PDB Entry: 2ab2, 1.85 Å

PDB Description: mineralocorticoid receptor double mutant with bound spironolactone

PDB Compounds: (B:) Mineralocorticoid receptor

SCOPe Domain Sequences for d2ab2b_:

Sequence, based on SEQRES records:

>d2ab2b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpqlstisraltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvvk
wakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmhq
samyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyike
lrkmvtkcpnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlve
iisdqlpkvesgnakplyfh

Sequence, based on observed residues (ATOM records):

>d2ab2b_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpqlstisraltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvvk
wakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmhq
samyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyike
lrkmvtcpnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlvei
isdqlpkvesgnakplyfh

Timeline for d2ab2b_:

• d2ab2b_ first appeared in SCOPe 2.03
  
• d2ab2b_ appears in SCOPe 2.06