SCOPe 2.08: Domain d2aaxa_: 2aax A:

Lineage for d2aaxa_ (2aax A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d2aaxa_: 2aax A: [203433]
   automated match to d2aa6b_
   complexed with pdn, so4; mutant

Details for d2aaxa_

PDB Entry: 2aax, 1.75 Å

PDB Description: mineralocorticoid receptor double mutant with bound cortisone

PDB Compounds: (A:) Mineralocorticoid receptor

SCOPe Domain Sequences for d2aaxa_:

Sequence, based on SEQRES records:

>d2aaxa_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alvpqlstisraltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvv
kwakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmh
qsamyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyik
elrkmvtkcpnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlv
eiisdqlpkvesgnakplyfhr

Sequence, based on observed residues (ATOM records):

>d2aaxa_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alvpqlstisraltpspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvv
kwakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmh
qsamyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyik
elrkmvtkcnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshalkvefpamlve
iisdqlpkvesgnakplyfhr

Timeline for d2aaxa_:

• d2aaxa_ first appeared in SCOPe 2.03
  
• d2aaxa_ appears in SCOPe 2.07