SCOP 1.73: Domain d1cfsb1: 1cfs B:1-112

Lineage for d1cfsb1 (1cfs B:1-112)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (148 PDB entries)

8. Domain d1cfsb1: 1cfs B:1-112 [20341]
   Other proteins in same PDB: d1cfsa1, d1cfsa2, d1cfsb2
   part of anti-gp120 (HIV-1) Fab CB 4-1

Details for d1cfsb1

PDB Entry: 1cfs, 2.75 Å

PDB Description: anti-p24 (hiv-1) fab fragment cb41 complexed with an epitope-unrelated peptide

PDB Compounds: (B:) protein (igg2a kappa antibody cb41 (heavy chain))

SCOP Domain Sequences for d1cfsb1:

Sequence; same for both SEQRES and ATOM records:

>d1cfsb1 b.1.1.1 (B:1-112) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
qdqlqqsgaelvrpgasvklsckalgyiftdyeihwvkqtpvhglewiggihpgssgtay
nqkfkgkatltadkssttafmelssltsedsavyyctrkdywgqgtlvtvsa

Timeline for d1cfsb1:

• d1cfsb1 first appeared (with stable ids) in SCOP 1.55
  
• d1cfsb1 appears in SCOP 1.71
  
• d1cfsb1 appears in SCOP 1.75
  
• d1cfsb1 appears in the current release, SCOPe 2.08