SCOPe 2.08: Domain d1zy4b1: 1zy4 B:594-983

Lineage for d1zy4b1 (1zy4 B:594-983)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187449] (23 PDB entries)

8. Domain d1zy4b1: 1zy4 B:594-983 [203371]
   Other proteins in same PDB: d1zy4a2, d1zy4b2
   automated match to d1zy5b_
   complexed with gol; mutant

Details for d1zy4b1

PDB Entry: 1zy4, 1.95 Å

PDB Description: crystal structure of eif2alpha protein kinase gcn2: r794g hyperactivating mutant in apo form.

PDB Compounds: (B:) Serine/threonine-protein kinase GCN2

SCOPe Domain Sequences for d1zy4b1:

Sequence, based on SEQRES records:

>d1zy4b1 d.144.1.0 (B:594-983) automated matches {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ryasdfeeiavlgqgafgqvvkarnaldsryyaikkirhteeklstilsevmllaslnhq
yvvryyaawlerrnfvkpmtavkkkstlfiqmeycengtlydlihsenlnqqrdeywrlf
rqilealsyihsqgiihrdlkpmnifidesrnvkigdfglaknvhrsldilkldsqnlpg
ssdnltsaigtamyvatevldgtghynekidmyslgiiffemiypfstgmervnilkklr
svsiefppdfddnkmkvekkiirllidhdpnkrpgartllnsgwlpv

Sequence, based on observed residues (ATOM records):

>d1zy4b1 d.144.1.0 (B:594-983) automated matches {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ryasdfeeiavlgqgafgqvvkarnaldsryyaikkirhteeklstilsevmllaslnhq
yvvryyaawlerrnfvkkstlfiqmeycengtlydlihsenlnqqrdeywrlfrqileal
syihsqgiihrdlkpmnifidesrnvkigdfgligtamyvatevlynekidmyslgiiff
emiypfstgmervnilkklrsvsiefppdfddnkmkvekkiirllidhdpnkrpgartll
nsgwlpv

Timeline for d1zy4b1:

• d1zy4b1 first appeared in SCOPe 2.03, called d1zy4b_
  
• d1zy4b1 appears in SCOPe 2.07