SCOPe 2.06: Domain d1zxmb1: 1zxm B:29-265

Lineage for d1zxmb1 (1zxm B:29-265)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.0: automated matches [227160] (1 protein)
   not a true family

6. Protein automated matches [226867] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225008] (12 PDB entries)

8. Domain d1zxmb1: 1zxm B:29-265 [203368]
   Other proteins in same PDB: d1zxma2, d1zxmb2
   automated match to d1pvgb2
   complexed with anp, mg

Details for d1zxmb1

PDB Entry: 1zxm, 1.87 Å

PDB Description: Human Topo IIa ATPase/AMP-PNP

PDB Compounds: (B:) DNA topoisomerase II, alpha isozyme

SCOPe Domain Sequences for d1zxmb1:

Sequence; same for both SEQRES and ATOM records:

>d1zxmb1 d.122.1.0 (B:29-265) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sveriyqkktqlehillrpdtyigsvelvtqqmwvydedvginyrevtfvpglykifdei
lvnaadnkqrdpkmscirvtidpennlisiwnngkgipvvehkvekmyvpalifgqllts
snydddekkvtggrngygaklcnifstkftvetasreykkmfkqtwmdnmgragemelkp
fngedytcitfqpdlskfkmqsldkdivalmvrraydiagstkdvkvflngnklpvk

Timeline for d1zxmb1:

• d1zxmb1 first appeared in SCOPe 2.03
  
• d1zxmb1 appears in SCOPe 2.05
  
• d1zxmb1 appears in SCOPe 2.07
  
• d1zxmb1 appears in the current release, SCOPe 2.08