Lineage for d1cz8y1 (1cz8 Y:1-123)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 546556Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 547079Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88554] (32 PDB entries)
  8. 547098Domain d1cz8y1: 1cz8 Y:1-123 [20329]
    Other proteins in same PDB: d1cz8h2, d1cz8l1, d1cz8l2, d1cz8v_, d1cz8w_, d1cz8x1, d1cz8x2, d1cz8y2
    part of humanized Fab-12 neutralizing VEGF; affinity matured
    complexed with so4; mutant

Details for d1cz8y1

PDB Entry: 1cz8 (more details), 2.4 Å

PDB Description: vascular endothelial growth factor in complex with an affinity matured antibody

SCOP Domain Sequences for d1cz8y1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1cz8y1 b.1.1.1 (Y:1-123) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 4}
evqlvesggglvqpggslrlscaasgydfthygmnwvrqapgkglewvgwintytgepty
aadfkrrftfsldtskstaylqmnslraedtavyycakypyyygtshwyfdvwgqgtlvt
vss

SCOP Domain Coordinates for d1cz8y1:

Click to download the PDB-style file with coordinates for d1cz8y1.
(The format of our PDB-style files is described here.)

Timeline for d1cz8y1: