Lineage for d1cz8y1 (1cz8 Y:1-123)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 218897Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 218898Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 218899Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (15 proteins)
  6. 218958Protein Immunoglobulin (variable domains of L and H chains) [48749] (228 species)
  7. 220252Species VEGF neutralizing Fab-12 (mouse), kappa L chain [48870] (2 PDB entries)
  8. 220260Domain d1cz8y1: 1cz8 Y:1-123 [20329]
    Other proteins in same PDB: d1cz8h2, d1cz8l2, d1cz8v_, d1cz8w_, d1cz8x2, d1cz8y2
    affinity matured
    complexed with so4; mutant

Details for d1cz8y1

PDB Entry: 1cz8 (more details), 2.4 Å

PDB Description: vascular endothelial growth factor in complex with an affinity matured antibody

SCOP Domain Sequences for d1cz8y1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1cz8y1 b.1.1.1 (Y:1-123) Immunoglobulin (variable domains of L and H chains) {VEGF neutralizing Fab-12 (mouse), kappa L chain}
evqlvesggglvqpggslrlscaasgydfthygmnwvrqapgkglewvgwintytgepty
aadfkrrftfsldtskstaylqmnslraedtavyycakypyyygtshwyfdvwgqgtlvt
vss

SCOP Domain Coordinates for d1cz8y1:

Click to download the PDB-style file with coordinates for d1cz8y1.
(The format of our PDB-style files is described here.)

Timeline for d1cz8y1: