SCOP 1.63: Domain d1cz8x1: 1cz8 X:1-107

Lineage for d1cz8x1 (1cz8 X:1-107)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (15 proteins)

6. Protein Immunoglobulin (variable domains of L and H chains) [48749] (228 species)

7. Species VEGF neutralizing Fab-12 (mouse), kappa L chain [48870] (2 PDB entries)

8. Domain d1cz8x1: 1cz8 X:1-107 [20328]
   Other proteins in same PDB: d1cz8h2, d1cz8l2, d1cz8v_, d1cz8w_, d1cz8x2, d1cz8y2

Details for d1cz8x1

PDB Entry: 1cz8, 2.4 Å

PDB Description: vascular endothelial growth factor in complex with an affinity matured antibody

SCOP Domain Sequences for d1cz8x1:

Sequence; same for both SEQRES and ATOM records:

>d1cz8x1 b.1.1.1 (X:1-107) Immunoglobulin (variable domains of L and H chains) {VEGF neutralizing Fab-12 (mouse), kappa L chain}
diqltqspsslsasvgdrvtitcsasqdisnylnwyqqkpgkapkvliyftsslhsgvps
rfsgsgsgtdftltisslqpedfatyycqqystvpwtfgqgtkveik

Timeline for d1cz8x1:

• d1cz8x1 first appeared (with stable ids) in SCOP 1.55
  
• d1cz8x1 appears in SCOP 1.61
  
• d1cz8x1 appears in SCOP 1.65
  
• d1cz8x1 appears in the current release, SCOPe 2.08