Lineage for d1fnsh1 (1fns H:215-336)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018105Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)
  8. 2018113Domain d1fnsh1: 1fns H:215-336 [20289]
    Other proteins in same PDB: d1fnsa1, d1fnsa2, d1fnsh2, d1fnsl1, d1fnsl2
    part of Fab NMC-4 blocking the von willebrand factor (vwf) a1 domain function

Details for d1fnsh1

PDB Entry: 1fns (more details), 2 Å

PDB Description: crystal structure of the von willebrand factor (vwf) a1 domain i546v mutant in complex with the function blocking fab nmc4
PDB Compounds: (H:) immunoglobulin nmc-4 igg1

SCOPe Domain Sequences for d1fnsh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fnsh1 b.1.1.1 (H:215-336) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}

SCOPe Domain Coordinates for d1fnsh1:

Click to download the PDB-style file with coordinates for d1fnsh1.
(The format of our PDB-style files is described here.)

Timeline for d1fnsh1: