Lineage for d2hmic1 (2hmi C:1-107)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2018294Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018893Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (217 PDB entries)
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7 ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! SQ NA # humanized antibody ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01642 21-115 # ! KV5I_MOUSE Ig kappa chain V-V region L7 precursor
  8. 2019133Domain d2hmic1: 2hmi C:1-107 [20274]
    Other proteins in same PDB: d2hmia1, d2hmia2, d2hmib_, d2hmic2, d2hmid1, d2hmid2
    part of Fab 28 against HIV-1 RT
    protein/DNA complex

Details for d2hmic1

PDB Entry: 2hmi (more details), 2.8 Å

PDB Description: hiv-1 reverse transcriptase/fragment of fab 28/dna complex
PDB Compounds: (C:) fab fragment of monoclonal antibody 28

SCOPe Domain Sequences for d2hmic1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hmic1 b.1.1.1 (C:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}

SCOPe Domain Coordinates for d2hmic1:

Click to download the PDB-style file with coordinates for d2hmic1.
(The format of our PDB-style files is described here.)

Timeline for d2hmic1: