SCOPe 2.05: Domain d4hvab_: 4hva B:

Lineage for d4hvab_ (4hva B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.0: automated matches [191651] (1 protein)
   not a true family

6. Protein automated matches [191201] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189525] (14 PDB entries)

8. Domain d4hvab_: 4hva B: [202491]
   automated match to d4hvaa_
   complexed with 4hv

Details for d4hvab_

PDB Entry: 4hva, 2.07 Å

PDB Description: Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6

PDB Compounds: (B:) Caspase-6

SCOPe Domain Sequences for d4hvab_:

Sequence, based on SEQRES records:

>d4hvab_ c.17.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mfdpaekykmdhrrrgialifnherffwhltlperrgtcadrdnltrrfsdlgfevkcfn
dlkaeelllkihevstvshadadcfvcvflshgegnhiyaydakieiqtltglfkgdkch
slvgkpkifiiqacrgnqhdvpvipldvvdaasvytlpagadflmcysvaegyyshretv
ngswyiqdlcemlgkygssleftelltlvnrkvsqrrvdfckdpsaigkkqvpcfasmlt
kklhffpk

Sequence, based on observed residues (ATOM records):

>d4hvab_ c.17.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mfdpaekykmdhrrrgialifnherffwhltlperrgtcadrdnltrrfsdlgfevkcfn
dlkaeelllkihevstvshadadcfvcvflshgegnhiyaydakieiqtltglfkgdkch
slvgkpkifiiqacrgnqhdvpviplvytlpagadflmcysvaegyyshretvngswyiq
dlcemlgkygssleftelltlvnrkvsqrrvdfckdpsaigkkqvpcfasmltkklhffp
k

Timeline for d4hvab_:

• d4hvab_ first appeared in SCOPe 2.03
  
• d4hvab_ appears in SCOPe 2.04
  
• d4hvab_ appears in SCOPe 2.06
  
• d4hvab_ appears in the current release, SCOPe 2.08