Lineage for d4h98a1 (4h98 A:4-217)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477520Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2477723Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2477724Species Candida glabrata [TaxId:284593] [237803] (4 PDB entries)
  8. 2477731Domain d4h98a1: 4h98 A:4-217 [202388]
    Other proteins in same PDB: d4h98a2, d4h98b2
    automated match to d4h98b_
    complexed with 14q, ndp

Details for d4h98a1

PDB Entry: 4h98 (more details), 2.9 Å

PDB Description: Candida glabrata dihydrofolate reductase complexed with NADPH and 5-{3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyphenyl]prop-1-yn-1-yl}-6-ethylpyrimidine-2,4-diamine (UCP1018)
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d4h98a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4h98a1 c.71.1.1 (A:4-217) Dihydrofolate reductases, eukaryotic type {Candida glabrata [TaxId: 284593]}

SCOPe Domain Coordinates for d4h98a1:

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Timeline for d4h98a1:

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