SCOP 1.67: Domain d1c1el1: 1c1e L:1-112

Lineage for d1c1el1 (1c1e L:1-112)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (22 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (24 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (121 PDB entries)

8. Domain d1c1el1: 1c1e L:1-112 [20238]
   Other proteins in same PDB: d1c1eh1, d1c1eh2, d1c1el2
   part of Diels-Alder catalytic Fab 1E9
   complexed with dmr, enh

Details for d1c1el1

PDB Entry: 1c1e, 1.9 Å

PDB Description: crystal structure of a diels-alderase catalytic antibody 1e9 in complex with its hapten

SCOP Domain Sequences for d1c1el1:

Sequence; same for both SEQRES and ATOM records:

>d1c1el1 b.1.1.1 (L:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
elvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspkfliykvsnrf
sgvpdrfggsgsgtdfilkisrveaedlgvyfcfqsthffptfgggtkleiksadaa

Timeline for d1c1el1:

• d1c1el1 first appeared (with stable ids) in SCOP 1.55
  
• d1c1el1 appears in SCOP 1.65
  
• d1c1el1 appears in SCOP 1.69
  
• d1c1el1 appears in the current release, SCOPe 2.08