Lineage for d1a4ja1 (1a4j A:1-112)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 651989Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)
  6. 652980Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 653172Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (127 PDB entries)
  8. 653254Domain d1a4ja1: 1a4j A:1-112 [20232]
    Other proteins in same PDB: d1a4ja2, d1a4jb1, d1a4jb2, d1a4jh1, d1a4jh2, d1a4jl2
    part of humanized Diels-Alder catalytic Fab; germline precursor

Details for d1a4ja1

PDB Entry: 1a4j (more details), 2.1 Å

PDB Description: diels alder catalytic antibody germline precursor
PDB Compounds: (A:) immunoglobulin, diels alder catalytic antibody (light chain)

SCOP Domain Sequences for d1a4ja1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1a4ja1 b.1.1.1 (A:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
elvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqsthvpptfgggtkleik

SCOP Domain Coordinates for d1a4ja1:

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Timeline for d1a4ja1: