Lineage for d1gpoh1 (1gpo H:1-113)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1287638Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1287642Species Engineered (including hybrid species) [88562] (68 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # humanized antibody ! SQ NA # Humanized antibody ! SQ NA # engineered antibody
  8. 1287657Domain d1gpoh1: 1gpo H:1-113 [20225]
    Other proteins in same PDB: d1gpoh2, d1gpoi2, d1gpol1, d1gpol2, d1gpom1, d1gpom2
    part of Fab M41 (artificial design)
    complexed with so4

Details for d1gpoh1

PDB Entry: 1gpo (more details), 1.95 Å

PDB Description: crystal structure of the rationally designed antibody m41 as a fab fragment
PDB Compounds: (H:) antibody m41

SCOPe Domain Sequences for d1gpoh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1gpoh1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}
evklqesgpslvkpsqtlsltcsvtgdsitsdfwswirqfpgnrleymgfvqysgetayn
pslksrisitrdtsknqyyldlnsvttedtavyycanwhgdywgqgttvtvss

SCOPe Domain Coordinates for d1gpoh1:

Click to download the PDB-style file with coordinates for d1gpoh1.
(The format of our PDB-style files is described here.)

Timeline for d1gpoh1: