SCOPe 2.08: Domain d4eosb1: 4eos B:176-309

Lineage for d4eosb1 (4eos B:176-309)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (4 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (9 proteins)

6. Protein Cyclin A [47956] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47957] (89 PDB entries)
   Uniprot P20248 175-432

8. Domain d4eosb1: 4eos B:176-309 [201929]
   Other proteins in same PDB: d4eosa1, d4eosa2, d4eosc1, d4eosc2
   automated match to d1h1pb1
   complexed with 1ro

Details for d4eosb1

PDB Entry: 4eos, 2.57 Å

PDB Description: Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor RO3306

PDB Compounds: (B:) Cyclin-A2

SCOPe Domain Sequences for d4eosb1:

Sequence; same for both SEQRES and ATOM records:

>d4eosb1 a.74.1.1 (B:176-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
pdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhla
vnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrme
hlvlkvltfdlaap

Timeline for d4eosb1:

• d4eosb1 first appeared in SCOPe 2.03
  
• d4eosb1 appears in SCOPe 2.07