SCOPe 2.03: Domain d4eooc_: 4eoo C:

Lineage for d4eooc_ (4eoo C:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (335 PDB entries)
   Uniprot P24941

8. Domain d4eooc_: 4eoo C: [201912]
   Other proteins in same PDB: d4eoob1, d4eoob2, d4eood1, d4eood2
   automated match to d4eooa_
   complexed with atp, mg, sgm

Details for d4eooc_

PDB Entry: 4eoo, 2.1 Å

PDB Description: Thr 160 phosphorylated CDK2 Q131E - human cyclin A3 complex with ATP

PDB Compounds: (C:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d4eooc_:

Sequence; same for both SEQRES and ATOM records:

>d4eooc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
gsmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkel
nhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafc
hshrvlhrdlkpenllintegaikladfglarafgvpvrtythevvtlwyrapeillgck
yystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykp
sfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d4eooc_:

• d4eooc_ is new in SCOPe 2.03-stable
  
• d4eooc_ appears in SCOPe 2.04
  
• d4eooc_ appears in the current release, SCOPe 2.08, called d4eooc1