SCOPe 2.05: Domain d4e5yb_: 4e5y B:

Lineage for d4e5yb_ (4e5y B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (203 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186944] (39 PDB entries)

8. Domain d4e5yb_: 4e5y B: [201801]
   automated match to d4e5yc_
   complexed with ndp

Details for d4e5yb_

PDB Entry: 4e5y, 2.37 Å

PDB Description: Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose

PDB Compounds: (B:) GDP-l-fucose synthase

SCOPe Domain Sequences for d4e5yb_:

Sequence, based on SEQRES records:

>d4e5yb_ c.2.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smrilvtggsglvgkaiqkvvadgaglpgedwvfvsskdadltdtaqtralfekvqpthv
ihlaamvgglfrnikynldfwrknvhmndnvlhsafevgarkvvsclstcifpdkttypi
detmihngpphnsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfniedgh
vlpglihkvhlakssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepiilsvge
edevsikeaaeavveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpfkqavk
etcawftdnyeqark

Sequence, based on observed residues (ATOM records):

>d4e5yb_ c.2.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smrilvtggsglvgkaiqkvvadgagedwvfvsskdadltdtaqtralfekvqpthvihl
aamvgglfrnikynldfwrknvhmndnvlhsafevgarkvvsclstcifpdkttypidet
mihngpphnsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfniedghvlp
glihkvhlakssgsltvwgtgnprrqfiysldlaqlfiwvlreynevepiilsvgeedev
sikeaaeavveamdfhgvtfdttksdqfkktasnsklrtylpdfrftpfkqavketcawf
tdnyeqark

Timeline for d4e5yb_:

• d4e5yb_ first appeared in SCOPe 2.03
  
• d4e5yb_ appears in SCOPe 2.04
  
• d4e5yb_ appears in SCOPe 2.06
  
• d4e5yb_ appears in the current release, SCOPe 2.08