SCOPe 2.08: Domain d4a5yb_: 4a5y B:

Lineage for d4a5yb_ (4a5y B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (5 proteins)

6. Protein Kinesin [52646] (7 species)

7. Species Human (Homo sapiens), mitotic kinesin eg5 [TaxId:9606] [64018] (15 PDB entries)

8. Domain d4a5yb_: 4a5y B: [201400]
   Other proteins in same PDB: d4a5ya_
   automated match to d1ii6a_
   complexed with adp, cl, g7x, mg, po4

Details for d4a5yb_

PDB Entry: 4a5y, 2.45 Å

PDB Description: intermediate state of human kinesin eg5 in complex with ispinesib

PDB Compounds: (B:) Kinesin-like protein KIF11

SCOPe Domain Sequences for d4a5yb_:

Sequence, based on SEQRES records:

>d4a5yb_ c.37.1.9 (B:) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelv
kigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyreskl
trilqdslggrtrtsiiatispaslnleetlstleyahraknilnk

Sequence, based on observed residues (ATOM records):

>d4a5yb_ c.37.1.9 (B:) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
kniqvvvrcrpfnahsivecdpvrkevsvktytfdmvfgastkqidvyrsvvcpildevi
mgynctifaygqtgtgktftmegerspneeytweedplagiiprtlhqifekltdngtef
svkvslleiyneelfdllnpssdvserlqmfddprnkrgviikgleeitvhnkdevyqil
ekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlagsennqslltlgrvit
alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
nk

Timeline for d4a5yb_:

• d4a5yb_ first appeared in SCOPe 2.03
  
• d4a5yb_ appears in SCOPe 2.07