SCOPe 2.08: Domain d3zgoa1: 3zgo A:34-356

Lineage for d3zgoa1 (3zgo A:34-356)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
   silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain

6. Protein automated matches [191258] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189817] (4 PDB entries)

8. Domain d3zgoa1: 3zgo A:34-356 [201313]
   Other proteins in same PDB: d3zgoa2, d3zgob2
   automated match to d3zgob_
   complexed with edo, eoh, p6g, pge, zn

Details for d3zgoa1

PDB Entry: 3zgo, 1.63 Å

PDB Description: re-refined structure of the human sirt2 apoform

PDB Compounds: (A:) nad-dependent protein deacetylase sirtuin-2

SCOPe Domain Sequences for d3zgoa1:

Sequence, based on SEQRES records:

>d3zgoa1 c.31.1.5 (A:34-356) automated matches {Human (Homo sapiens) [TaxId: 9606]}
geadmdflrnlfsqtlslgsqkerlldeltlegvarymqsercrrviclvgagistsagi
pdfrspstglydnlekyhlpypeaifeisyfkkhpepffalakelypgqfkptichyfmr
llkdkglllrcytqnidtleriagleqedlveahgtfytshcvsascrheyplswmkeki
fsevtpkcedcqslvkpdivffgespparffscmqsdflkvdlllvmgtslqvqpfasli
skaplstprllinkekagqsdpflgmimglgggmdfdskkayrdvawlgecdqgclalae
llgwkkeledlvrrehasidaqs

Sequence, based on observed residues (ATOM records):

>d3zgoa1 c.31.1.5 (A:34-356) automated matches {Human (Homo sapiens) [TaxId: 9606]}
geadmdflrnlfsqkerlldeltlegvarymqsercrrviclvgagistsagipdfrsps
tglydnlekyhlpypeaifeisyfkkhpepffalakelypgqfkptichyfmrllkdkgl
llrcytqnidtleriagleqedlveahgtfytshcvsascrheyplswmkekifsevtpk
cedcqslvkpdivffgespparffscmqsdflkvdlllvmgtslqvqpfasliskaplst
prllinkekagqsdpflgmimglgggmdfdskkayrdvawlgecdqgclalaellgwkke
ledlvrrehasidaqs

Timeline for d3zgoa1:

• d3zgoa1 first appeared in SCOPe 2.03, called d3zgoa_
  
• d3zgoa1 appears in SCOPe 2.07