SCOPe 2.08: Domain d1clol1: 1clo L:1-107

Lineage for d1clol1 (1clo L:1-107)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.3 [TaxId:10090] [88529] (2 PDB entries)

8. Domain d1clol1: 1clo L:1-107 [20122]
   Other proteins in same PDB: d1cloh1, d1cloh2, d1clol2
   part of Fab A5B7

Details for d1clol1

PDB Entry: 1clo, 2.1 Å

PDB Description: anti-carcinoembryonic antigen monoclonal antibody a5b7

PDB Compounds: (L:) a5b7 monoclonal antibody

SCOPe Domain Sequences for d1clol1:

Sequence; same for both SEQRES and ATOM records:

>d1clol1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 3.3 [TaxId: 10090]}
qtvlsqspailsaspgekvtmtcrasssvtyihwyqqkpgsspkswiyatsnlasgvpar
fsgsgsgtsysltisrveaedaatyycqhwsskpptfgggtkleik

Timeline for d1clol1:

• d1clol1 first appeared (with stable ids) in SCOP 1.55
  
• d1clol1 appears in SCOPe 2.07