Lineage for d2rcsl1 (2rcs L:1-109)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2018294Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018893Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (217 PDB entries)
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7 ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! SQ NA # humanized antibody ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01642 21-115 # ! KV5I_MOUSE Ig kappa chain V-V region L7 precursor
  8. 2018979Domain d2rcsl1: 2rcs L:1-109 [20086]
    Other proteins in same PDB: d2rcsh1, d2rcsh2, d2rcsl2
    part of humanized Fab 48G7

Details for d2rcsl1

PDB Entry: 2rcs (more details), 2.1 Å

PDB Description: immunoglobulin 48g7 germline fab-affinity maturation of an esterolytic antibody
PDB Compounds: (L:) immunoglobulin 48g7 germline fab

SCOPe Domain Sequences for d2rcsl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2rcsl1 b.1.1.1 (L:1-109) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}

SCOPe Domain Coordinates for d2rcsl1:

Click to download the PDB-style file with coordinates for d2rcsl1.
(The format of our PDB-style files is described here.)

Timeline for d2rcsl1:

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