Lineage for d3ro9a1 (3ro9 A:3-217)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2137011Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2137012Species Candida glabrata [TaxId:284593] [237803] (4 PDB entries)
  8. 2137017Domain d3ro9a1: 3ro9 A:3-217 [200501]
    Other proteins in same PDB: d3ro9a2, d3ro9b2
    automated match to d3ro9b_
    complexed with 06u, ndp

Details for d3ro9a1

PDB Entry: 3ro9 (more details), 2.6 Å

PDB Description: Candida glabrata dihydrofolate reductase complexed with NADPH and 6-ethyl-5-[(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1006)
PDB Compounds: (A:) Strain CBS138 chromosome J complete sequence

SCOPe Domain Sequences for d3ro9a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3ro9a1 c.71.1.1 (A:3-217) Dihydrofolate reductases, eukaryotic type {Candida glabrata [TaxId: 284593]}

SCOPe Domain Coordinates for d3ro9a1:

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Timeline for d3ro9a1:

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