SCOPe 2.08: Domain d3qrja1: 3qrj A:246-496

Lineage for d3qrja1 (3qrj A:246-496)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3qrja1: 3qrj A:246-496 [200374]
   Other proteins in same PDB: d3qrja2, d3qrjb2
   automated match to d3qrjb_
   complexed with 919; mutant

Details for d3qrja1

PDB Entry: 3qrj, 1.82 Å

PDB Description: The crystal structure of human abl1 kinase domain T315I mutant in complex with DCC-2036

PDB Compounds: (A:) Tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3qrja1:

Sequence, based on SEQRES records:

>d3qrja1 d.144.1.7 (A:246-496) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmkeikhpnlvqllgvc
treppfyiiiefmtygnlldylrecnrqevnavvllymatqissameylekknfihrdla
arnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkfsiksdvwaf
gvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwqwnpsdrps
faeihqafetm

Sequence, based on observed residues (ATOM records):

>d3qrja1 d.144.1.7 (A:246-496) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hklgggqygevyegvwkkysltvavktleveeflkeaavmkeikhpnlvqllgvctrepp
fyiiiefmtygnlldylrecnrqevnavvllymatqissameylekknfihrdlaarncl
vgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkfsiksdvwafgvllw
eiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwqwnpsdrpsfaeih
qafetm

Timeline for d3qrja1:

• d3qrja1 first appeared in SCOPe 2.03, called d3qrja_
  
• d3qrja1 appears in SCOPe 2.07