Lineage for d1ikfh1 (1ikf H:1-126)

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 287095Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 287096Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 287097Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)
  6. 287195Protein Immunoglobulin heavy chain variable domain, VH [88543] (19 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogeneous CDRs are listed as engineered species
  7. 287316Species Mouse (Mus musculus), cluster 2.2 [TaxId:10090] [88550] (47 PDB entries)
  8. 287332Domain d1ikfh1: 1ikf H:1-126 [20033]
    Other proteins in same PDB: d1ikfh2, d1ikfl1, d1ikfl2
    part of an anti-cyclosporin A Fab
    complexed with aba

Details for d1ikfh1

PDB Entry: 1ikf (more details), 2.5 Å

PDB Description: a conformation of cyclosporin a in aqueous environment revealed by the x-ray structure of a cyclosporin-fab complex
PDB Compounds: (H:)

SCOP Domain Sequences for d1ikfh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ikfh1 b.1.1.1 (H:1-126) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 2.2}
evklvesggglvqpggslklscatsgftfsdyymywvrqnsekrlewvafisngggsafy
adivkgrftisrdnakntlylqmsrlksedtamyyctrhtlydtlygnypvwfadwgqgt
lvtvsa

SCOP Domain Coordinates for d1ikfh1:

Click to download the PDB-style file with coordinates for d1ikfh1.
(The format of our PDB-style files is described here.)

Timeline for d1ikfh1:

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Domains from same chain:
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d1ikfh2