Lineage for d1ncch1 (1ncc H:1-113)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018055Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88554] (34 PDB entries)
    Uniprot P06327 20-117 # HV52_MOUSE (P06327) Ig heavy chain V region VH558 A1/A4 precursor; 57% sequence identity ! Uniprot P01631 # KV2G_MOUSE (P01631) Ig kappa chain V-II region 26-10
  8. 2018081Domain d1ncch1: 1ncc H:1-113 [19987]
    Other proteins in same PDB: d1ncch2, d1nccl1, d1nccl2, d1nccn_
    part of Fab NC41
    complexed with ca, nag; mutant

Details for d1ncch1

PDB Entry: 1ncc (more details), 2.5 Å

PDB Description: crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface
PDB Compounds: (H:) igg2a-kappa nc41 fab (heavy chain)

SCOPe Domain Sequences for d1ncch1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ncch1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}

SCOPe Domain Coordinates for d1ncch1:

Click to download the PDB-style file with coordinates for d1ncch1.
(The format of our PDB-style files is described here.)

Timeline for d1ncch1: