SCOPe 2.06: Domain d1g7lb_: 1g7l B:

Lineage for d1g7lb_ (1g7l B:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)

8. Domain d1g7lb_: 1g7l B: [19959]
   Other proteins in same PDB: d1g7la_, d1g7lc_
   part of Fv D1.3
   mutant

Details for d1g7lb_

PDB Entry: 1g7l, 2 Å

PDB Description: crystal structure of hen egg white lysozyme (hel) complexed with the mutant anti-hel monoclonal antibody d1.3 (vlw92s)

PDB Compounds: (B:) anti-hen egg white lysozyme monoclonal antibody d1.3

SCOPe Domain Sequences for d1g7lb_:

Sequence, based on SEQRES records:

>d1g7lb_ b.1.1.1 (B:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltv

Sequence, based on observed residues (ATOM records):

>d1g7lb_ b.1.1.1 (B:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdynsalk
srlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltv

Timeline for d1g7lb_:

• d1g7lb_ first appeared (with stable ids) in SCOP 1.55
  
• d1g7lb_ appears in SCOPe 2.05
  
• d1g7lb_ appears in SCOPe 2.07
  
• d1g7lb_ appears in the current release, SCOPe 2.08