Lineage for d1g7lb_ (1g7l B:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2739730Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2740504Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)
  8. 2740533Domain d1g7lb_: 1g7l B: [19959]
    Other proteins in same PDB: d1g7la_, d1g7lc_
    part of Fv D1.3
    mutant

Details for d1g7lb_

PDB Entry: 1g7l (more details), 2 Å

PDB Description: crystal structure of hen egg white lysozyme (hel) complexed with the mutant anti-hel monoclonal antibody d1.3 (vlw92s)
PDB Compounds: (B:) anti-hen egg white lysozyme monoclonal antibody d1.3

SCOPe Domain Sequences for d1g7lb_:

Sequence, based on SEQRES records: (download)

>d1g7lb_ b.1.1.1 (B:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltv

Sequence, based on observed residues (ATOM records): (download)

>d1g7lb_ b.1.1.1 (B:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdynsalk
srlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltv

SCOPe Domain Coordinates for d1g7lb_:

Click to download the PDB-style file with coordinates for d1g7lb_.
(The format of our PDB-style files is described here.)

Timeline for d1g7lb_: