SCOP 1.67: Domain d1g7ha_: 1g7h A:

Lineage for d1g7ha_ (1g7h A:)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (22 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (24 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (160 PDB entries)

8. Domain d1g7ha_: 1g7h A: [19948]
   Other proteins in same PDB: d1g7hb_, d1g7hc_
   part of Fv D1.3
   mutant

Details for d1g7ha_

PDB Entry: 1g7h, 1.85 Å

PDB Description: crystal structure of hen egg white lysozyme (hel) complexed with the mutant anti-hel monoclonal antibody d1.3(vlw92a)

SCOP Domain Sequences for d1g7ha_:

Sequence; same for both SEQRES and ATOM records:

>d1g7ha_ b.1.1.1 (A:) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
divltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvyytttladgvps
rfsgsgsgtqyslkinslqpedfgsyycqhfastprtfgggtkleik

Timeline for d1g7ha_:

• d1g7ha_ first appeared (with stable ids) in SCOP 1.55
  
• d1g7ha_ appears in SCOP 1.65
  
• d1g7ha_ appears in SCOP 1.69
  
• d1g7ha_ appears in the current release, SCOPe 2.08