SCOPe 2.03: Domain d3gw9b_: 3gw9 B:

Lineage for d3gw9b_ (3gw9 B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (33 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [194968] (6 PDB entries)

8. Domain d3gw9b_: 3gw9 B: [199475]
   automated match to d3gw9d_
   complexed with hem, vni

Details for d3gw9b_

PDB Entry: 3gw9, 1.87 Å

PDB Description: crystal structure of sterol 14-alpha demethylase (cyp51) from trypanosoma brucei bound to an inhibitor n-(1-(2,4-dichlorophenyl)-2- (1h-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxaziazol-2-yl)benzamide

PDB Compounds: (B:) sterol 14alpha-demethylase

SCOPe Domain Sequences for d3gw9b_:

Sequence; same for both SEQRES and ATOM records:

>d3gw9b_ a.104.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gklppvypvtvpilghiiqfgksplgfmqeckrqlksgiftinivgkrvtivgdphehsr
fflprnevlsprevysfmvpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqh
evrkfmaanwdkdegeinlledcstmiintacqclfgedlrkrldarrfaqllakmessl
ipaavflpillklplpqsarcheartelqkilseiiiarkeeevnkdsstsdllsgllsa
vyrdgtpmslhevcgmivaamfagqhtssitttwsmlhlmhpanvkhlealrkeieefpa
qlnynnvmdempfaercaresirrdppllmlmrkvmadvkvgsyvvpkgdiiacspllsh
hdeeafpeprrwdperdekvegafigfgagvhkcigqkfgllqvktilatafrsydfqll
rdevpdpdyhtmvvgptasqcrvkyirrk

Timeline for d3gw9b_:

• d3gw9b_ is new in SCOPe 2.03-stable
  
• d3gw9b_ appears in SCOPe 2.04
  
• d3gw9b_ appears in the current release, SCOPe 2.08