SCOPe 2.01: Domain d1a7oh_: 1a7o H:

Lineage for d1a7oh_ (1a7o H:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)

8. Domain d1a7oh_: 1a7o H: [19943]
   Other proteins in same PDB: d1a7ol_
   part of Fv D1.3
   mutant

Details for d1a7oh_

PDB Entry: 1a7o, 2 Å

PDB Description: fv fragment of mouse monoclonal antibody d1.3 (balb/c, igg1, k) r96l deletion mutant on variant for chain l glu81->asp and chain h leu312->val

PDB Compounds: (H:) igg1-kappa d1.3 fv (heavy chain)

SCOPe Domain Sequences for d1a7oh_:

Sequence; same for both SEQRES and ATOM records:

>d1a7oh_ b.1.1.1 (H:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttvtvss

Timeline for d1a7oh_:

• d1a7oh_ first appeared (with stable ids) in SCOP 1.55
  
• d1a7oh_ appears in SCOP 1.75
  
• d1a7oh_ appears in SCOPe 2.02
  
• d1a7oh_ appears in the current release, SCOPe 2.08