SCOPe 2.08: Domain d3et1a_: 3et1 A:

Lineage for d3et1a_ (3et1 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69110] (30 PDB entries)

8. Domain d3et1a_: 3et1 A: [199374]
   automated match to d3et1b_
   protein/DNA complex; complexed with et1

Details for d3et1a_

PDB Entry: 3et1, 2.5 Å

PDB Description: Structure of PPARalpha with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid

PDB Compounds: (A:) Peroxisome proliferator-activated receptor alpha

SCOPe Domain Sequences for d3et1a_:

Sequence, based on SEQRES records:

>d3et1a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
etadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvakl
vangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaif
amlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislf
vaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvt
ehaqlvqiikktesdaalhpllqeiyrdmy

Sequence, based on observed residues (ATOM records):

>d3et1a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
etadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvaqn
keaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifamlssvm
nkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaaiicc
gdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvtehaqlvq
iikktesdaalhpllqeiyrdmy

Timeline for d3et1a_:

• d3et1a_ first appeared in SCOPe 2.03
  
• d3et1a_ appears in SCOPe 2.07