Lineage for d1frgh1 (1frg H:218-336)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 651989Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)
  6. 652160Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 652445Species Mouse (Mus musculus), cluster 2.2 [TaxId:10090] [88550] (51 PDB entries)
  8. 652477Domain d1frgh1: 1frg H:218-336 [19925]
    Other proteins in same PDB: d1frgh2, d1frgl1, d1frgl2
    part of Fab 26/9
    complexed with nh2

Details for d1frgh1

PDB Entry: 1frg (more details), 2.8 Å

PDB Description: crystal structure, sequence, and epitope mapping of a peptide complex of an anti-influenza ha peptide antibody fab 26(slash)9: fine-tuning antibody specificity
PDB Compounds: (H:) igg2a 26/9 fab (heavy chain)

SCOP Domain Sequences for d1frgh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1frgh1 b.1.1.1 (H:218-336) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 2.2 [TaxId: 10090]}
evllvesggdlvkpggflklscaasgftfssfgmswvrhtpdkrlewvatisngggytyy
qdsvkgrftisrdnakntlflemtslksedaglyycarrerydekgfaywgrgtlvtvs

SCOP Domain Coordinates for d1frgh1:

Click to download the PDB-style file with coordinates for d1frgh1.
(The format of our PDB-style files is described here.)

Timeline for d1frgh1:

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Domains from same chain:
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d1frgh2