Lineage for d2ig2h1 (2ig2 H:1-119)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017500Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (33 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)
  8. 2017568Domain d2ig2h1: 2ig2 H:1-119 [19849]
    Other proteins in same PDB: d2ig2h2, d2ig2l1, d2ig2l2
    part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure

Details for d2ig2h1

PDB Entry: 2ig2 (more details), 3 Å

PDB Description: dir primaerstruktur des kristallisierbaren monoklonalen immunoglobulins igg1 kol. ii. aminosaeuresequenz der l-kette, lambda-typ, subgruppe i (german)
PDB Compounds: (H:) igg1-lambda kol fab (heavy chain)

SCOPe Domain Sequences for d2ig2h1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ig2h1 b.1.1.1 (H:1-119) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 3 [TaxId: 9606]}

SCOPe Domain Coordinates for d2ig2h1:

Click to download the PDB-style file with coordinates for d2ig2h1.
(The format of our PDB-style files is described here.)

Timeline for d2ig2h1:

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