Lineage for d2ig2l1 (2ig2 L:1-109)

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 287095Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 287096Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 287097Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)
  6. 288276Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (8 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 288285Species Human (Homo sapiens), cluster 2 [TaxId:9606] [88536] (6 PDB entries)
  8. 288294Domain d2ig2l1: 2ig2 L:1-109 [19848]
    Other proteins in same PDB: d2ig2h1, d2ig2h2, d2ig2l2
    part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure

Details for d2ig2l1

PDB Entry: 2ig2 (more details), 3 Å

PDB Description: dir primaerstruktur des kristallisierbaren monoklonalen immunoglobulins igg1 kol. ii. aminosaeuresequenz der l-kette, lambda- typ, subgruppe i (german)

SCOP Domain Sequences for d2ig2l1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ig2l1 b.1.1.1 (L:1-109) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 2}

SCOP Domain Coordinates for d2ig2l1:

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Timeline for d2ig2l1:

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