Lineage for d1igmh_ (1igm H:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2739730Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2739899Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (30 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)
  8. 2739939Domain d1igmh_: 1igm H: [19827]
    Other proteins in same PDB: d1igml_
    part of IgM Fv POT

Details for d1igmh_

PDB Entry: 1igm (more details), 2.3 Å

PDB Description: three dimensional structure of an fv from a human igm immunoglobulin
PDB Compounds: (H:) igm-kappa pot fv (heavy chain)

SCOPe Domain Sequences for d1igmh_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1igmh_ b.1.1.1 (H:) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 3 [TaxId: 9606]}
evhllesggnlvqpggslrlscaasgftfnifvmswvrqapgkglewvsgvfgsggntdy
adavkgrftitrdnskntlylqmnslraedtaiyycakhrvsyvltgfdswgqgtlvtvs
sgsasaptl

SCOPe Domain Coordinates for d1igmh_:

Click to download the PDB-style file with coordinates for d1igmh_.
(The format of our PDB-style files is described here.)

Timeline for d1igmh_:

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d1igml_